{"id":184,"date":"2024-07-01T14:08:42","date_gmt":"2024-07-01T14:08:42","guid":{"rendered":"https:\/\/clinpharmacolgroup.es\/dermatomics\/?page_id=184"},"modified":"2024-07-01T14:08:42","modified_gmt":"2024-07-01T14:08:42","slug":"d2","status":"publish","type":"page","link":"https:\/\/clinpharmacolgroup.es\/dermatomics\/index.php\/d2\/","title":{"rendered":"D2"},"content":{"rendered":"<p>[et_pb_section fb_built=\u00bb1&#8243; next_background_color=\u00bb#ffffff\u00bb admin_label=\u00bbFeature\u00bb _builder_version=\u00bb4.25.1&#8243; background_color=\u00bb#E09900&#8243; use_background_color_gradient=\u00bbon\u00bb background_color_gradient_stops=\u00bb#7f4600 5%|rgba(219,219,219,0) 100%\u00bb background_color_gradient_overlays_image=\u00bbon\u00bb background_color_gradient_start=\u00bb#345168&#8243; background_color_gradient_start_position=\u00bb5%\u00bb background_color_gradient_end=\u00bbrgba(219,219,219,0)\u00bb background_image=\u00bbhttps:\/\/clinpharmacolgroup.es\/dermatomics\/wp-content\/uploads\/2024\/07\/derma6.jpg\u00bb custom_padding=\u00bb5%||10%||false|false\u00bb bottom_divider_style=\u00bbslant\u00bb bottom_divider_flip=\u00bbhorizontal\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_row column_structure=\u00bb1_2,1_2&#8243; _builder_version=\u00bb4.16&#8243; max_width=\u00bb1280px\u00bb animation_direction=\u00bbbottom\u00bb use_custom_width=\u00bbon\u00bb custom_width_px=\u00bb1280px\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_column type=\u00bb1_2&#8243; _builder_version=\u00bb4.16&#8243; custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_text admin_label=\u00bbText\u00bb _builder_version=\u00bb4.25.1&#8243; text_font=\u00bbLato||||||||\u00bb text_font_size=\u00bb18px\u00bb text_line_height=\u00bb1.8em\u00bb link_font=\u00bb||||||||\u00bb ul_font=\u00bb||||||||\u00bb ol_font=\u00bb||||||||\u00bb quote_font=\u00bb||||||||\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bbLato|700|||||||\u00bb header_2_font_size=\u00bb40px\u00bb header_2_letter_spacing=\u00bb2px\u00bb header_2_line_height=\u00bb1.5em\u00bb header_3_font=\u00bb||||||||\u00bb header_4_font=\u00bb||||||||\u00bb header_5_font=\u00bb||||||||\u00bb header_6_font=\u00bbLato|700|||||||\u00bb header_6_font_size=\u00bb18px\u00bb header_6_letter_spacing=\u00bb1px\u00bb header_6_line_height=\u00bb1.8em\u00bb text_orientation=\u00bbright\u00bb background_layout=\u00bbdark\u00bb animation_style=\u00bbslide\u00bb animation_direction=\u00bbbottom\u00bb animation_intensity_slide=\u00bb5%\u00bb header_2_font_size_tablet=\u00bb\u00bb header_2_font_size_phone=\u00bb22px\u00bb header_2_font_size_last_edited=\u00bbon|phone\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb]<\/p>\n<h6>OBJETIVOS<\/h6>\n<h2>DERMATOMICS II<\/h2>\n<p>El objetivo general del estudio es optimizar el tratamiento de pacientes con dermatitis at\u00f3pica moderada-grave que requieran tratamiento sist\u00e9mico tras fracaso, intolerancia o contraindicaci\u00f3n a ciclosporina. Teniendo como objetivos principales:<\/p>\n<p>1) Identificar biomarcadores gen\u00e9ticos, bioqu\u00edmicos e inmunol\u00f3gicos que permitan seleccionar la alternativa terap\u00e9utica m\u00e1s adecuada en cada paciente y desarrollar un modelo de predicci\u00f3n a partir de dichos biomarcadores.<\/p>\n<p>2) Optimizar la terapia en pacientes con enfermedad at\u00f3pica que requieren tratamiento sist\u00e9mico de segunda l\u00ednea mediante el desarrollo de modelos predictivos de respuesta que incorporen variables gen\u00e9ticas, inmunol\u00f3gicas, bioqu\u00edmicas, cl\u00ednicas y demogr\u00e1ficas.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00bb1_2&#8243; _builder_version=\u00bb4.16&#8243; custom_padding=\u00bb10%|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_blurb title=\u00bbSe realiza en el Hospital La Paz en colaboraci\u00f3n con el Servicio de Dermatolog\u00eda\u00bb use_icon=\u00bbon\u00bb font_icon=\u00bb&#xe052;||divi||400&#8243; icon_color=\u00bb#ffffff\u00bb icon_placement=\u00bbleft\u00bb image_icon_width=\u00bb22px\u00bb content_max_width=\u00bb1100px\u00bb _builder_version=\u00bb4.21.0&#8243; header_font=\u00bbLato||||||||\u00bb header_font_size=\u00bb16px\u00bb header_line_height=\u00bb1.4em\u00bb background_layout=\u00bbdark\u00bb custom_margin=\u00bb||0px|\u00bb animation_style=\u00bbslide\u00bb animation_direction=\u00bbbottom\u00bb animation_intensity_slide=\u00bb5%\u00bb icon_font_size=\u00bb22px\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][\/et_pb_blurb][et_pb_blurb title=\u00bbEl estudio se divide en dos cohortes:\u00bb use_icon=\u00bbon\u00bb font_icon=\u00bb&#xe052;||divi||400&#8243; icon_color=\u00bb#ffffff\u00bb icon_placement=\u00bbleft\u00bb image_icon_width=\u00bb22px\u00bb content_max_width=\u00bb1100px\u00bb _builder_version=\u00bb4.25.1&#8243; header_font=\u00bbLato||||||||\u00bb header_font_size=\u00bb16px\u00bb header_line_height=\u00bb1.4em\u00bb background_layout=\u00bbdark\u00bb custom_margin=\u00bb||0px|\u00bb animation_style=\u00bbslide\u00bb animation_direction=\u00bbbottom\u00bb animation_intensity_slide=\u00bb5%\u00bb icon_font_size=\u00bb22px\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb]<\/p>\n<p><strong>Cohorte 1:<\/strong> Se seleccionar\u00e1n todos los pacientes diagnosticados de dermatitis at\u00f3pica moderada-grave que vayan a recibir tratamiento de segunda l\u00ednea.<\/p>\n<p><strong>Cohorte 2<\/strong>: Se seleccionar\u00e1n todos los pacientes con diagn\u00f3stico de dermatitis at\u00f3pica moderada-grave que est\u00e9n recibiendo tratamiento de segunda l\u00ednea.<\/p>\n<p>[\/et_pb_blurb][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\u00bb1&#8243; admin_label=\u00bbAbout\u00bb _builder_version=\u00bb4.21.0&#8243; background_enable_image=\u00bboff\u00bb background_position=\u00bbtop_right\u00bb custom_padding=\u00bb28px|0px|28px|0px|true|false\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_row column_structure=\u00bb1_2,1_2&#8243; _builder_version=\u00bb4.16&#8243; use_custom_width=\u00bbon\u00bb locked=\u00bboff\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_column type=\u00bb1_2&#8243; _builder_version=\u00bb4.16&#8243; custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_text admin_label=\u00bbText\u00bb _builder_version=\u00bb4.25.1&#8243; text_font=\u00bbLato||||||||\u00bb text_font_size=\u00bb18px\u00bb text_line_height=\u00bb1.8em\u00bb link_font=\u00bb||||||||\u00bb ul_font=\u00bb||||||||\u00bb ol_font=\u00bb||||||||\u00bb quote_font=\u00bb||||||||\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bbLato|700|||||||\u00bb header_2_font_size=\u00bb40px\u00bb header_2_letter_spacing=\u00bb1px\u00bb header_2_line_height=\u00bb1.5em\u00bb header_3_font=\u00bb||||||||\u00bb header_4_font=\u00bb||||||||\u00bb header_5_font=\u00bb||||||||\u00bb header_6_font=\u00bbLato|700|||||||\u00bb header_6_font_size=\u00bb18px\u00bb header_6_letter_spacing=\u00bb1px\u00bb header_6_line_height=\u00bb1.8em\u00bb text_orientation=\u00bbright\u00bb header_2_font_size_tablet=\u00bb\u00bb header_2_font_size_phone=\u00bb22px\u00bb header_2_font_size_last_edited=\u00bbon|phone\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb]<\/p>\n<h2>RESULTADOS<\/h2>\n<p>El estudio se encuentra actualmente en fase de reclutamiento y no se ha comenzado a\u00fan el an\u00e1lisis de resultados. El primer paciente fue incluido el 28 de septiembre de 2023.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00bb1_2&#8243; _builder_version=\u00bb4.16&#8243; custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_image src=\u00bbhttps:\/\/clinpharmacolgroup.es\/dermatomics\/wp-content\/uploads\/2024\/07\/derma2.jpg\u00bb title_text=\u00bbderma2&#8243; _builder_version=\u00bb4.25.1&#8243; _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][\/et_pb_image][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\u00bb1&#8243; custom_padding_last_edited=\u00bbon|phone\u00bb prev_background_color=\u00bb#ffffff\u00bb admin_label=\u00bbBlank Section &#8211; Image Background\u00bb _builder_version=\u00bb4.25.1&#8243; background_image=\u00bbhttps:\/\/clinpharmacolgroup.es\/dermatomics\/wp-content\/uploads\/2024\/07\/FONDO.jpg\u00bb custom_padding=\u00bb4.6%||4.6%||true|false\u00bb custom_padding_tablet=\u00bb260px||260px||true\u00bb custom_padding_phone=\u00bb100px|||\u00bb top_divider_style=\u00bbslant\u00bb top_divider_flip=\u00bbhorizontal\u00bb bottom_divider_style=\u00bbslant\u00bb bottom_divider_color=\u00bb#f5f5f5&#8243; bottom_divider_flip=\u00bbhorizontal\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_row use_custom_gutter=\u00bbon\u00bb gutter_width=\u00bb1&#8243; _builder_version=\u00bb4.16&#8243; custom_margin=\u00bb|||\u00bb custom_padding=\u00bb0px||0px||true\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_column type=\u00bb4_4&#8243; _builder_version=\u00bb4.16&#8243; custom_padding=\u00bb|||\u00bb global_colors_info=\u00bb{}\u00bb custom_padding__hover=\u00bb|||\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_text _builder_version=\u00bb4.25.1&#8243; _module_preset=\u00bbdefault\u00bb background_color=\u00bb#ffb356&#8243; min_height=\u00bb332.2px\u00bb custom_margin=\u00bb-96px||159px|||\u00bb custom_padding=\u00bb106px|40px|0px|40px|false|false\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb]<\/p>\n<h2><span style=\"color: #ffffff;\"><strong>CONCLUSIONES DERMATOMICS II<\/strong><\/span><\/h2>\n<p>\n<span style=\"color: #ffffff;\">Existe la necesidad de optimizar el manejo de la dermatitis at\u00f3pica para mejorar la eficacia de los tratamientos y reducir la toxicidad asociada con ellos.<\/span>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\u00bb1&#8243; 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text_font=\u00bbLato||||||||\u00bb text_font_size=\u00bb18px\u00bb text_line_height=\u00bb1.8em\u00bb link_font=\u00bb||||||||\u00bb ul_font=\u00bb||||||||\u00bb ol_font=\u00bb||||||||\u00bb quote_font=\u00bb||||||||\u00bb header_font=\u00bb||||||||\u00bb header_2_font=\u00bbLato|700|||||||\u00bb header_2_font_size=\u00bb40px\u00bb header_2_letter_spacing=\u00bb2px\u00bb header_2_line_height=\u00bb1.5em\u00bb header_3_font=\u00bb||||||||\u00bb header_4_font=\u00bb||||||||\u00bb header_5_font=\u00bb||||||||\u00bb header_6_font=\u00bbLato|700|||||||\u00bb header_6_font_size=\u00bb18px\u00bb header_6_letter_spacing=\u00bb1px\u00bb header_6_line_height=\u00bb1.8em\u00bb text_orientation=\u00bbright\u00bb background_layout=\u00bbdark\u00bb max_width=\u00bb600px\u00bb module_alignment=\u00bbright\u00bb animation_style=\u00bbslide\u00bb animation_direction=\u00bbbottom\u00bb animation_intensity_slide=\u00bb5%\u00bb header_2_font_size_tablet=\u00bb\u00bb header_2_font_size_phone=\u00bb22px\u00bb header_2_font_size_last_edited=\u00bbon|phone\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb]<\/p>\n<h2>\u00bfHas participado en el ensayo y quieres darnos tu opini\u00f3n?<\/h2>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00bb1_2&#8243; _builder_version=\u00bb4.16&#8243; custom_padding=\u00bb5%|6%|10%|6%\u00bb custom_padding_tablet=\u00bb||150px|\u00bb custom_padding_phone=\u00bb||150px|\u00bb custom_padding_last_edited=\u00bbon|tablet\u00bb global_colors_info=\u00bb{}\u00bb padding_tablet=\u00bb||150px|\u00bb padding_last_edited=\u00bbon|tablet\u00bb custom_padding__hover=\u00bb|||\u00bb padding_phone=\u00bb||150px|\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_text _builder_version=\u00bb4.21.0&#8243; text_font=\u00bbLato||||||||\u00bb text_font_size=\u00bb18px\u00bb text_line_height=\u00bb1.8em\u00bb background_layout=\u00bbdark\u00bb max_width=\u00bb600px\u00bb animation_style=\u00bbslide\u00bb animation_direction=\u00bbbottom\u00bb animation_intensity_slide=\u00bb5%\u00bb text_font_size_tablet=\u00bb\u00bb text_font_size_phone=\u00bb\u00bb text_font_size_last_edited=\u00bbon|tablet\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb]<\/p>\n<p>Si has participado en el ensayo, y quieres darnos tu opini\u00f3n o hacernos alguna sugerencia, puedes escribirnos.<\/p>\n<p>Gracias por participar<\/p>\n<p>[\/et_pb_text][et_pb_button button_url=\u00bb@ET-DC@eyJkeW5hbWljIjp0cnVlLCJjb250ZW50IjoicG9zdF9saW5rX3VybF9wYWdlIiwic2V0dGluZ3MiOnsicG9zdF9pZCI6IjYzIn19@\u00bb button_text=\u00bb\u00a1Escr\u00edbenos!\u00bb button_alignment=\u00bbright\u00bb _builder_version=\u00bb4.21.0&#8243; 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Cont\u00e1ctanos<\/h2>\n<p>[\/et_pb_text][dvppl_cf7_styler cf7=\u00bb68&#8243; _builder_version=\u00bb4.21.0&#8243; _module_preset=\u00bbdefault\u00bb form_field_font_text_color=\u00bb#FFFFFF\u00bb labels_text_color=\u00bb#FFFFFF\u00bb custom_submit_button=\u00bbon\u00bb submit_button_text_size=\u00bb16px\u00bb submit_button_text_color=\u00bb#FFFFFF\u00bb submit_button_bg_color=\u00bb#E09900&#8243; submit_button_border_width=\u00bb0px\u00bb submit_button_font=\u00bb||||||||\u00bb box_shadow_style_submit_button=\u00bbpreset2&#8243; global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][\/dvppl_cf7_styler][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=\u00bb1&#8243; _builder_version=\u00bb4.21.0&#8243; _module_preset=\u00bbdefault\u00bb background_color=\u00bbRGBA(255,255,255,0)\u00bb use_background_color_gradient=\u00bbon\u00bb background_color_gradient_direction=\u00bb123deg\u00bb background_color_gradient_stops=\u00bb#d6d6d6 0%|#2ea6c9 79%\u00bb custom_margin=\u00bb||||false|false\u00bb global_module=\u00bb88&#8243; saved_tabs=\u00bball\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_row column_structure=\u00bb1_3,1_3,1_3&#8243; _builder_version=\u00bb4.19.4&#8243; _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_column type=\u00bb1_3&#8243; _builder_version=\u00bb4.19.4&#8243; _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_image src=\u00bbhttps:\/\/clinpharmacolgroup.es\/dermatomics\/wp-content\/uploads\/2023\/06\/logoDermatomics2.png\u00bb title_text=\u00bblogoDermatomics2&#8243; _builder_version=\u00bb4.21.0&#8243; _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][\/et_pb_image][\/et_pb_column][et_pb_column type=\u00bb1_3&#8243; _builder_version=\u00bb4.19.4&#8243; _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_text _builder_version=\u00bb4.21.0&#8243; _module_preset=\u00bbdefault\u00bb text_text_color=\u00bb#FFFFFF\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb]<\/p>\n<p><strong>Investigador principal Dermatomics I:<\/strong><\/p>\n<p>Dr. Alberto M. Borobia<\/p>\n<p><b>Investigador principal Dermatomics II<\/b><\/p>\n<p>Irene Garc\u00eda<\/p>\n<p><b>Subinvestigador<\/b><\/p>\n<p>Alicia Mar\u00edn<\/p>\n<p><b>Gestor del proyecto<\/b><\/p>\n<p>Roc\u00edo Prieto<\/p>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=\u00bb1_3&#8243; _builder_version=\u00bb4.19.4&#8243; _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_text _builder_version=\u00bb4.19.4&#8243; _module_preset=\u00bbdefault\u00bb text_text_color=\u00bb#FFFFFF\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb]<\/p>\n<p><strong>Hospital Universitario La Paz<\/strong><\/p>\n<p>Servicio de Farmacolog\u00eda Cl\u00ednica \u2013 UCICEC<\/p>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row _builder_version=\u00bb4.19.4&#8243; _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_column type=\u00bb4_4&#8243; _builder_version=\u00bb4.19.4&#8243; _module_preset=\u00bbdefault\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb][et_pb_text _builder_version=\u00bb4.21.0&#8243; _module_preset=\u00bbdefault\u00bb text_text_color=\u00bb#FFFFFF\u00bb global_colors_info=\u00bb{}\u00bb theme_builder_area=\u00bbpost_content\u00bb]<\/p>\n<p><span>\u00a9 Copyright 2023\u00a0\u00a0\u00a0|\u00a0 \u00a0Dermatopics Todos los derechos reservados<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>OBJETIVOS DERMATOMICS II El objetivo general del estudio es optimizar el tratamiento de pacientes con dermatitis at\u00f3pica moderada-grave que requieran tratamiento sist\u00e9mico tras fracaso, intolerancia o contraindicaci\u00f3n a ciclosporina. 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